Sedatromin
Brand names,
Sedatromin
Analogs
Sedatromin
Brand Names Mixture
Sedatromin
Chemical_Formula
C26H28N2
Sedatromin
RX_link
No information avaliable
Sedatromin
fda sheet
Sedatromin
msds (material safety sheet)
Sedatromin
Synthesis Reference
No information avaliable
Sedatromin
Molecular Weight
368.514 g/mol
Sedatromin
Melting Point
No information avaliable
Sedatromin
H2O Solubility
750 mg/L
Sedatromin
State
Solid
Sedatromin
LogP
5.63
Sedatromin
Dosage Forms
No information avaliable
Sedatromin
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Sedatromin
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Sedatromin
Absorption
No information avaliable
Sedatromin
side effects and Toxicity
No information avaliable
Sedatromin
Patient Information
No information avaliable
Sedatromin
Organisms Affected
Humans and other mammals