Marisan
Brand names,
Marisan
Analogs
Marisan
Brand Names Mixture
Marisan
Chemical_Formula
C26H28N2
Marisan
RX_link
No information avaliable
Marisan
fda sheet
Marisan
msds (material safety sheet)
Marisan
Synthesis Reference
No information avaliable
Marisan
Molecular Weight
368.514 g/mol
Marisan
Melting Point
No information avaliable
Marisan
H2O Solubility
750 mg/L
Marisan
State
Solid
Marisan
LogP
5.63
Marisan
Dosage Forms
No information avaliable
Marisan
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Marisan
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Marisan
Absorption
No information avaliable
Marisan
side effects and Toxicity
No information avaliable
Marisan
Patient Information
No information avaliable
Marisan
Organisms Affected
Humans and other mammals