Artate
Brand names,
Artate
Analogs
Artate
Brand Names Mixture
Artate
Chemical_Formula
C26H28N2
Artate
RX_link
No information avaliable
Artate
fda sheet
Artate
msds (material safety sheet)
Artate
Synthesis Reference
No information avaliable
Artate
Molecular Weight
368.514 g/mol
Artate
Melting Point
No information avaliable
Artate
H2O Solubility
750 mg/L
Artate
State
Solid
Artate
LogP
5.63
Artate
Dosage Forms
No information avaliable
Artate
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Artate
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Artate
Absorption
No information avaliable
Artate
side effects and Toxicity
No information avaliable
Artate
Patient Information
No information avaliable
Artate
Organisms Affected
Humans and other mammals