Folcodal
Brand names,
Folcodal
Analogs
Folcodal
Brand Names Mixture
Folcodal
Chemical_Formula
C26H28N2
Folcodal
RX_link
No information avaliable
Folcodal
fda sheet
Folcodal
msds (material safety sheet)
Folcodal
Synthesis Reference
No information avaliable
Folcodal
Molecular Weight
368.514 g/mol
Folcodal
Melting Point
No information avaliable
Folcodal
H2O Solubility
750 mg/L
Folcodal
State
Solid
Folcodal
LogP
5.63
Folcodal
Dosage Forms
No information avaliable
Folcodal
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Folcodal
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Folcodal
Absorption
No information avaliable
Folcodal
side effects and Toxicity
No information avaliable
Folcodal
Patient Information
No information avaliable
Folcodal
Organisms Affected
Humans and other mammals