Labyrin
Brand names,
Labyrin
Analogs
Labyrin
Brand Names Mixture
Labyrin
Chemical_Formula
C26H28N2
Labyrin
RX_link
No information avaliable
Labyrin
fda sheet
Labyrin
msds (material safety sheet)
Labyrin
Synthesis Reference
No information avaliable
Labyrin
Molecular Weight
368.514 g/mol
Labyrin
Melting Point
No information avaliable
Labyrin
H2O Solubility
750 mg/L
Labyrin
State
Solid
Labyrin
LogP
5.63
Labyrin
Dosage Forms
No information avaliable
Labyrin
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Labyrin
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Labyrin
Absorption
No information avaliable
Labyrin
side effects and Toxicity
No information avaliable
Labyrin
Patient Information
No information avaliable
Labyrin
Organisms Affected
Humans and other mammals