Apotomin
Brand names,
Apotomin
Analogs
Apotomin
Brand Names Mixture
Apotomin
Chemical_Formula
C26H28N2
Apotomin
RX_link
No information avaliable
Apotomin
fda sheet
Apotomin
msds (material safety sheet)
Apotomin
Synthesis Reference
No information avaliable
Apotomin
Molecular Weight
368.514 g/mol
Apotomin
Melting Point
No information avaliable
Apotomin
H2O Solubility
750 mg/L
Apotomin
State
Solid
Apotomin
LogP
5.63
Apotomin
Dosage Forms
No information avaliable
Apotomin
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Apotomin
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Apotomin
Absorption
No information avaliable
Apotomin
side effects and Toxicity
No information avaliable
Apotomin
Patient Information
No information avaliable
Apotomin
Organisms Affected
Humans and other mammals