Giganten
Brand names,
Giganten
Analogs
Giganten
Brand Names Mixture
Giganten
Chemical_Formula
C26H28N2
Giganten
RX_link
No information avaliable
Giganten
fda sheet
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msds (material safety sheet)
Giganten
Synthesis Reference
No information avaliable
Giganten
Molecular Weight
368.514 g/mol
Giganten
Melting Point
No information avaliable
Giganten
H2O Solubility
750 mg/L
Giganten
State
Solid
Giganten
LogP
5.63
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Dosage Forms
No information avaliable
Giganten
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Giganten
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Giganten
Absorption
No information avaliable
Giganten
side effects and Toxicity
No information avaliable
Giganten
Patient Information
No information avaliable
Giganten
Organisms Affected
Humans and other mammals