Siptazin
Brand names,
Siptazin
Analogs
Siptazin
Brand Names Mixture
Siptazin
Chemical_Formula
C26H28N2
Siptazin
RX_link
No information avaliable
Siptazin
fda sheet
Siptazin
msds (material safety sheet)
Siptazin
Synthesis Reference
No information avaliable
Siptazin
Molecular Weight
368.514 g/mol
Siptazin
Melting Point
No information avaliable
Siptazin
H2O Solubility
750 mg/L
Siptazin
State
Solid
Siptazin
LogP
5.63
Siptazin
Dosage Forms
No information avaliable
Siptazin
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Siptazin
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Siptazin
Absorption
No information avaliable
Siptazin
side effects and Toxicity
No information avaliable
Siptazin
Patient Information
No information avaliable
Siptazin
Organisms Affected
Humans and other mammals