Dimitron
Brand names,
Dimitron
Analogs
Dimitron
Brand Names Mixture
Dimitron
Chemical_Formula
C26H28N2
Dimitron
RX_link
No information avaliable
Dimitron
fda sheet
Dimitron
msds (material safety sheet)
Dimitron
Synthesis Reference
No information avaliable
Dimitron
Molecular Weight
368.514 g/mol
Dimitron
Melting Point
No information avaliable
Dimitron
H2O Solubility
750 mg/L
Dimitron
State
Solid
Dimitron
LogP
5.63
Dimitron
Dosage Forms
No information avaliable
Dimitron
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Dimitron
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Dimitron
Absorption
No information avaliable
Dimitron
side effects and Toxicity
No information avaliable
Dimitron
Patient Information
No information avaliable
Dimitron
Organisms Affected
Humans and other mammals