Hilactan
Brand names,
Hilactan
Analogs
Hilactan
Brand Names Mixture
Hilactan
Chemical_Formula
C26H28N2
Hilactan
RX_link
No information avaliable
Hilactan
fda sheet
Hilactan
msds (material safety sheet)
Hilactan
Synthesis Reference
No information avaliable
Hilactan
Molecular Weight
368.514 g/mol
Hilactan
Melting Point
No information avaliable
Hilactan
H2O Solubility
750 mg/L
Hilactan
State
Solid
Hilactan
LogP
5.63
Hilactan
Dosage Forms
No information avaliable
Hilactan
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Hilactan
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Hilactan
Absorption
No information avaliable
Hilactan
side effects and Toxicity
No information avaliable
Hilactan
Patient Information
No information avaliable
Hilactan
Organisms Affected
Humans and other mammals