Mitronal
Brand names,
Mitronal
Analogs
Mitronal
Brand Names Mixture
Mitronal
Chemical_Formula
C26H28N2
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
Mitronal
Molecular Weight
368.514 g/mol
Mitronal
Melting Point
No information avaliable
Mitronal
H2O Solubility
750 mg/L
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State
Solid
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LogP
5.63
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Dosage Forms
No information avaliable
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Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Mitronal
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Mitronal
Absorption
No information avaliable
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side effects and Toxicity
No information avaliable
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Patient Information
No information avaliable
Mitronal
Organisms Affected
Humans and other mammals