Denapol
Brand names,
Denapol
Analogs
Denapol
Brand Names Mixture
Denapol
Chemical_Formula
C26H28N2
Denapol
RX_link
No information avaliable
Denapol
fda sheet
Denapol
msds (material safety sheet)
Denapol
Synthesis Reference
No information avaliable
Denapol
Molecular Weight
368.514 g/mol
Denapol
Melting Point
No information avaliable
Denapol
H2O Solubility
750 mg/L
Denapol
State
Solid
Denapol
LogP
5.63
Denapol
Dosage Forms
No information avaliable
Denapol
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Denapol
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Denapol
Absorption
No information avaliable
Denapol
side effects and Toxicity
No information avaliable
Denapol
Patient Information
No information avaliable
Denapol
Organisms Affected
Humans and other mammals