Cinnageron
Brand names,
Cinnageron
Analogs
Cinnageron
Brand Names Mixture
Cinnageron
Chemical_Formula
C26H28N2
Cinnageron
RX_link
No information avaliable
Cinnageron
fda sheet
Cinnageron
msds (material safety sheet)
Cinnageron
Synthesis Reference
No information avaliable
Cinnageron
Molecular Weight
368.514 g/mol
Cinnageron
Melting Point
No information avaliable
Cinnageron
H2O Solubility
750 mg/L
Cinnageron
State
Solid
Cinnageron
LogP
5.63
Cinnageron
Dosage Forms
No information avaliable
Cinnageron
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Cinnageron
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Cinnageron
Absorption
No information avaliable
Cinnageron
side effects and Toxicity
No information avaliable
Cinnageron
Patient Information
No information avaliable
Cinnageron
Organisms Affected
Humans and other mammals