Lazeta
Brand names,
Lazeta
Analogs
Lazeta
Brand Names Mixture
Lazeta
Chemical_Formula
C26H28N2
Lazeta
RX_link
No information avaliable
Lazeta
fda sheet
Lazeta
msds (material safety sheet)
Lazeta
Synthesis Reference
No information avaliable
Lazeta
Molecular Weight
368.514 g/mol
Lazeta
Melting Point
No information avaliable
Lazeta
H2O Solubility
750 mg/L
Lazeta
State
Solid
Lazeta
LogP
5.63
Lazeta
Dosage Forms
No information avaliable
Lazeta
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Lazeta
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Lazeta
Absorption
No information avaliable
Lazeta
side effects and Toxicity
No information avaliable
Lazeta
Patient Information
No information avaliable
Lazeta
Organisms Affected
Humans and other mammals