Cinnarizin
Brand names,
Cinnarizin
Analogs
Cinnarizin
Brand Names Mixture
Cinnarizin
Chemical_Formula
C26H28N2
Cinnarizin
RX_link
No information avaliable
Cinnarizin
fda sheet
Cinnarizin
msds (material safety sheet)
Cinnarizin
Synthesis Reference
No information avaliable
Cinnarizin
Molecular Weight
368.514 g/mol
Cinnarizin
Melting Point
No information avaliable
Cinnarizin
H2O Solubility
750 mg/L
Cinnarizin
State
Solid
Cinnarizin
LogP
5.63
Cinnarizin
Dosage Forms
No information avaliable
Cinnarizin
Indication
For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
Cinnarizin
Pharmacology
Cinnarizine is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizine also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizine through its calcium channel blocking ability also inhibits stimulation of the vestibular system.
Cinnarizin
Absorption
No information avaliable
Cinnarizin
side effects and Toxicity
No information avaliable
Cinnarizin
Patient Information
No information avaliable
Cinnarizin
Organisms Affected
Humans and other mammals