Propoxyphene
Propoxyphene Brand names, Propoxyphene Analogs
Propoxyphene Brand Names Mixture
- No information avaliable
Propoxyphene Chemical_Formula
C22H29NO2
Propoxyphene RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Propoxyphene fda sheet
Propoxyphene msds (material safety sheet)
Propoxyphene Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Propoxyphene Molecular Weight
339.471 g/mol
Propoxyphene Melting Point
75-76oC
Propoxyphene H2O Solubility
19.6mg/L
Propoxyphene State
Solid
Propoxyphene LogP
4.901
Propoxyphene Dosage Forms
Tablet
Propoxyphene Indication
For the relief of mild to moderate pain
Propoxyphene Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Propoxyphene Absorption
No information avaliable
Propoxyphene side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Propoxyphene Patient Information
Propoxyphene Organisms Affected
Humans and other mammals
