Algafan
Brand names,
Algafan
Analogs
Algafan
Brand Names Mixture
Algafan
Chemical_Formula
C22H29NO2
Algafan
RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Algafan
fda sheet
Algafan
msds (material safety sheet)
Algafan
Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Algafan
Molecular Weight
339.471 g/mol
Algafan
Melting Point
75-76oC
Algafan
H2O Solubility
19.6mg/L
Algafan
State
Solid
Algafan
LogP
4.901
Algafan
Dosage Forms
Tablet
Algafan
Indication
For the relief of mild to moderate pain
Algafan
Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Algafan
Absorption
No information avaliable
Algafan
side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Algafan
Patient Information
Algafan
Organisms Affected
Humans and other mammals