Darvon-N
Brand names,
Darvon-N
Analogs
Darvon-N
Brand Names Mixture
Darvon-N
Chemical_Formula
C22H29NO2
Darvon-N
RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Darvon-N
fda sheet
Darvon-N
msds (material safety sheet)
Darvon-N
Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Darvon-N
Molecular Weight
339.471 g/mol
Darvon-N
Melting Point
75-76oC
Darvon-N
H2O Solubility
19.6mg/L
Darvon-N
State
Solid
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LogP
4.901
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Dosage Forms
Tablet
Darvon-N
Indication
For the relief of mild to moderate pain
Darvon-N
Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Darvon-N
Absorption
No information avaliable
Darvon-N
side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Darvon-N
Patient Information
Darvon-N
Organisms Affected
Humans and other mammals