Kesso-Gesic
Kesso-Gesic Brand names, Kesso-Gesic Analogs
Kesso-Gesic Brand Names Mixture
- No information avaliable
Kesso-Gesic Chemical_Formula
C22H29NO2
Kesso-Gesic RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Kesso-Gesic fda sheet
Kesso-Gesic msds (material safety sheet)
Kesso-Gesic Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Kesso-Gesic Molecular Weight
339.471 g/mol
Kesso-Gesic Melting Point
75-76oC
Kesso-Gesic H2O Solubility
19.6mg/L
Kesso-Gesic State
Solid
Kesso-Gesic LogP
4.901
Kesso-Gesic Dosage Forms
Tablet
Kesso-Gesic Indication
For the relief of mild to moderate pain
Kesso-Gesic Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Kesso-Gesic Absorption
No information avaliable
Kesso-Gesic side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Kesso-Gesic Patient Information
Kesso-Gesic Organisms Affected
Humans and other mammals
