Dextropropoxyphene-M
Dextropropoxyphene-M Brand names, Dextropropoxyphene-M Analogs
Dextropropoxyphene-M Brand Names Mixture
- No information avaliable
Dextropropoxyphene-M Chemical_Formula
C22H29NO2
Dextropropoxyphene-M RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Dextropropoxyphene-M fda sheet
Dextropropoxyphene-M msds (material safety sheet)
Dextropropoxyphene-M Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Dextropropoxyphene-M Molecular Weight
339.471 g/mol
Dextropropoxyphene-M Melting Point
75-76oC
Dextropropoxyphene-M H2O Solubility
19.6mg/L
Dextropropoxyphene-M State
Solid
Dextropropoxyphene-M LogP
4.901
Dextropropoxyphene-M Dosage Forms
Tablet
Dextropropoxyphene-M Indication
For the relief of mild to moderate pain
Dextropropoxyphene-M Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Dextropropoxyphene-M Absorption
No information avaliable
Dextropropoxyphene-M side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Dextropropoxyphene-M Patient Information
Dextropropoxyphene-M Organisms Affected
Humans and other mammals
