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Darvocet Brand names, Darvocet Analogs

Darvocet Brand Names Mixture

  • Amacodone (acetaminophen + hydrocodone bitartrate)
  • Anexsia (acetaminophen + hydrocodone bitartrate)
  • Anodynos (acetaminophen + hydrocodone bitartrate)
  • Anolor (acetaminophen + butalbital + caffeine)
  • Bancap (acetaminophen + hydrocodone bitartrate)
  • CoGesic (acetaminophen + hydrocodone bitartrate)
  • Dolacet (acetaminophen + hydrocodone bitartrate)
  • Duradyne (acetaminophen + hydrocodone bitartrate)
  • Endolor (acetaminophen + butalbital + caffeine)
  • Esgic (acetaminophen + butalbital + caffeine)
  • Fioricet (acetaminophen + butalbital + caffeine)
  • Hydrocet (acetaminophen + hydrocodone bitartrate)
  • Hydrogesic (acetaminophen + hydrocodone bitartrate)
  • Margesic (acetaminophen + hydrocodone bitartrate)
  • Lorcet (acetaminophen + hydrocodone bitartrate)
  • Lortab (acetaminophen + hydrocodone bitartrate)
  • Norcet (acetaminophen + hydrocodone bitartrate)
  • Oxycet (acetaminophen + oxycodone hydrochloride)
  • Percocet (acetaminophen + oxycodone hydrochloride)
  • Roxicet (acetaminophen + oxycodone hydrochloride)
  • Roxilox (acetaminophen + oxycodone hydrochloride)
  • Stagesic (acetaminophen + hydrocodone bitartrate)
  • TGesic (acetaminophen + hydrocodone bitartrate)
  • Tylox (acetaminophen + oxycodone hydrochloride)
  • Vicodin (acetaminophen + hydrocodone bitartrate)
  • Zebutal (acetaminophen + butalbital + caffeine)
  • Zydone (acetaminophen + hydrocodone bitartrate)

Darvocet Chemical_Formula

C8H9NO2

Darvocet RX_link

http://www.rxlist.com/cgi/generic/apap.htm

Darvocet fda sheet

Darvocet FDA

Darvocet msds (material safety sheet)

Darvocet MSDS

Darvocet Synthesis Reference

Pearson et al., J. Am .Chem. Soc. 75, 5907 (1953)

Darvocet Molecular Weight

151.163 g/mol

Darvocet Melting Point

169-170.5oC

Darvocet H2O Solubility

14 mg/mL (very slightly soluble in cold water; considerably more soluble in hot water)

Darvocet State

Solid

Darvocet LogP

0.917

Darvocet Dosage Forms

Capsule; Drops; Elixir; Liquid; Solution; Suspension; Syrup; Tablet; Tablet (effervescent)

Darvocet Indication

For temporary relief of fever and minor aches and pains.

Darvocet Pharmacology

Acetaminophen (USAN) or Paracetamol (INN) is a popular analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. It is a major ingredient in numerous cold and flu medications and many prescription analgesics. It is extremely safe in standard doses, but because of its wide availability, deliberate or accidental overdoses are not uncommon. Acetaminophen, unlike other common analgesics such as aspirin and ibuprofen, has no anti-inflammatory properties or effects on platelet function, and so it is not a member of the class of drugs known as non-steroidal anti-inflammatory drugs or NSAIDs. In normal doses acetaminophen does not irritate the lining of the stomach nor affect blood coagulation, the kidneys, or the fetal ductus arteriosus (as NSAIDs can). Like NSAIDs and unlike opioid analgesics, acetaminophen does not cause euphoria or alter mood in any way. Acetaminophen and NSAIDs have the benefit of being completely free of problems with addiction, dependence, tolerance and withdrawal. Acetaminophen is used on its own or in combination with pseudoephedrine, dextromethorphan, chlorpheniramine, diphenhydramine, doxylamine, codeine, hydrocodone, or oxycodone.

Darvocet Absorption

Rapid and almost complete

Darvocet side effects and Toxicity

Oral, mouse: LD50 = 338 mg/kg; Oral, rat: LD50 = 1944 mg/kg. Acetaminophen is metabolized primarily in the liver, where most of it is converted to inactive compounds by conjugation with sulfate and glucuronide, and then excreted by the kidneys. Only a small portion is metabolized via the hepatic cytochrome P450 enzyme system. The toxic effects of acetaminophen are due to a minor alkylating metabolite (N-acetyl-p-benzo-quinone imine), not acetaminophen itself nor any of the major metabolites. This toxic metabolite reacts with sulfhydryl groups. At usual doses, it is quickly detoxified by combining irreversibly with the sulfhydryl group of glutathione to produce a non-toxic conjugate that is eventually excreted by the kidneys. The toxic dose of paracetamol is highly variable. In adults, single doses above 10 grams or 140 mg/kg have a reasonable likelihood of causing toxicity. In adults, single doses of more than 25 grams have a high risk of lethality.

Darvocet Patient Information

Do not use the maximum dosage of this product for more than 10 days except under the advice
and supervision of a physician. Do not take the product for pain for more than 10 days,
or for fever for more than 3 days unless directed by a physician. If pain or fever persists
or gets worse, if new symptoms occur, or if redness or swelling is present, consult a
physician because these could be signs of a serious condition. Do not use with other
products containing acetaminophen.
Do not use if carton is opened. Keep this and all medication out of The reach of children.
As with any drug, if you are pregnant or nursing A baby, seek the advice of a health
professional before using this product. In the case of accidental overdose, contact a
doctor or a poison control Center immediately. Prompt medical attention is critical for
adults as Well as for children even if you do not notice any signs or symptoms.

Darvocet Organisms Affected

Humans and other mammals