Propoxyphene HCl 65
Brand names,
Propoxyphene HCl 65
Analogs
Propoxyphene HCl 65
Brand Names Mixture
Propoxyphene HCl 65
Chemical_Formula
C22H29NO2
Propoxyphene HCl 65
RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Propoxyphene HCl 65
fda sheet
Propoxyphene HCl 65
msds (material safety sheet)
Propoxyphene HCl 65
Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Propoxyphene HCl 65
Molecular Weight
339.471 g/mol
Propoxyphene HCl 65
Melting Point
75-76oC
Propoxyphene HCl 65
H2O Solubility
19.6mg/L
Propoxyphene HCl 65
State
Solid
Propoxyphene HCl 65
LogP
4.901
Propoxyphene HCl 65
Dosage Forms
Tablet
Propoxyphene HCl 65
Indication
For the relief of mild to moderate pain
Propoxyphene HCl 65
Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Propoxyphene HCl 65
Absorption
No information avaliable
Propoxyphene HCl 65
side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Propoxyphene HCl 65
Patient Information
Propoxyphene HCl 65
Organisms Affected
Humans and other mammals