Femadol
Brand names,
Femadol
Analogs
Femadol
Brand Names Mixture
Femadol
Chemical_Formula
C22H29NO2
Femadol
RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Femadol
fda sheet
Femadol
msds (material safety sheet)
Femadol
Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Femadol
Molecular Weight
339.471 g/mol
Femadol
Melting Point
75-76oC
Femadol
H2O Solubility
19.6mg/L
Femadol
State
Solid
Femadol
LogP
4.901
Femadol
Dosage Forms
Tablet
Femadol
Indication
For the relief of mild to moderate pain
Femadol
Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Femadol
Absorption
No information avaliable
Femadol
side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Femadol
Patient Information
Femadol
Organisms Affected
Humans and other mammals