Proxagesic
Proxagesic Brand names, Proxagesic Analogs
Proxagesic Brand Names Mixture
- No information avaliable
Proxagesic Chemical_Formula
C22H29NO2
Proxagesic RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Proxagesic fda sheet
Proxagesic msds (material safety sheet)
Proxagesic Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Proxagesic Molecular Weight
339.471 g/mol
Proxagesic Melting Point
75-76oC
Proxagesic H2O Solubility
19.6mg/L
Proxagesic State
Solid
Proxagesic LogP
4.901
Proxagesic Dosage Forms
Tablet
Proxagesic Indication
For the relief of mild to moderate pain
Proxagesic Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Proxagesic Absorption
No information avaliable
Proxagesic side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Proxagesic Patient Information
Proxagesic Organisms Affected
Humans and other mammals
