Propoxychel
Brand names,
Propoxychel
Analogs
Propoxychel
Brand Names Mixture
Propoxychel
Chemical_Formula
C22H29NO2
Propoxychel
RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Propoxychel
fda sheet
Propoxychel
msds (material safety sheet)
Propoxychel
Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Propoxychel
Molecular Weight
339.471 g/mol
Propoxychel
Melting Point
75-76oC
Propoxychel
H2O Solubility
19.6mg/L
Propoxychel
State
Solid
Propoxychel
LogP
4.901
Propoxychel
Dosage Forms
Tablet
Propoxychel
Indication
For the relief of mild to moderate pain
Propoxychel
Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Propoxychel
Absorption
No information avaliable
Propoxychel
side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Propoxychel
Patient Information
Propoxychel
Organisms Affected
Humans and other mammals