Darvon
Brand names,
Darvon
Analogs
Darvon
Brand Names Mixture
Darvon
Chemical_Formula
C22H29NO2
Darvon
RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Darvon
fda sheet
Darvon
msds (material safety sheet)
Darvon
Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Darvon
Molecular Weight
339.471 g/mol
Darvon
Melting Point
75-76oC
Darvon
H2O Solubility
19.6mg/L
Darvon
State
Solid
Darvon
LogP
4.901
Darvon
Dosage Forms
Tablet
Darvon
Indication
For the relief of mild to moderate pain
Darvon
Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Darvon
Absorption
No information avaliable
Darvon
side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Darvon
Patient Information
Darvon
Organisms Affected
Humans and other mammals