Dolocap
Brand names,
Dolocap
Analogs
Dolocap
Brand Names Mixture
Dolocap
Chemical_Formula
C22H29NO2
Dolocap
RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Dolocap
fda sheet
Dolocap
msds (material safety sheet)
Dolocap
Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Dolocap
Molecular Weight
339.471 g/mol
Dolocap
Melting Point
75-76oC
Dolocap
H2O Solubility
19.6mg/L
Dolocap
State
Solid
Dolocap
LogP
4.901
Dolocap
Dosage Forms
Tablet
Dolocap
Indication
For the relief of mild to moderate pain
Dolocap
Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Dolocap
Absorption
No information avaliable
Dolocap
side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Dolocap
Patient Information
Dolocap
Organisms Affected
Humans and other mammals