Doloxene
Doloxene Brand names, Doloxene Analogs
Doloxene Brand Names Mixture
- No information avaliable
Doloxene Chemical_Formula
C22H29NO2
Doloxene RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Doloxene fda sheet
Doloxene msds (material safety sheet)
Doloxene Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Doloxene Molecular Weight
339.471 g/mol
Doloxene Melting Point
75-76oC
Doloxene H2O Solubility
19.6mg/L
Doloxene State
Solid
Doloxene LogP
4.901
Doloxene Dosage Forms
Tablet
Doloxene Indication
For the relief of mild to moderate pain
Doloxene Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Doloxene Absorption
No information avaliable
Doloxene side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Doloxene Patient Information
Doloxene Organisms Affected
Humans and other mammals
