Dextropropoxyphene
Dextropropoxyphene Brand names, Dextropropoxyphene Analogs
Dextropropoxyphene Brand Names Mixture
- No information avaliable
Dextropropoxyphene Chemical_Formula
C22H29NO2
Dextropropoxyphene RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Dextropropoxyphene fda sheet
Dextropropoxyphene msds (material safety sheet)
Dextropropoxyphene Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Dextropropoxyphene Molecular Weight
339.471 g/mol
Dextropropoxyphene Melting Point
75-76oC
Dextropropoxyphene H2O Solubility
19.6mg/L
Dextropropoxyphene State
Solid
Dextropropoxyphene LogP
4.901
Dextropropoxyphene Dosage Forms
Tablet
Dextropropoxyphene Indication
For the relief of mild to moderate pain
Dextropropoxyphene Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Dextropropoxyphene Absorption
No information avaliable
Dextropropoxyphene side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Dextropropoxyphene Patient Information
Dextropropoxyphene Organisms Affected
Humans and other mammals
