Dextroproxifeno
Dextroproxifeno Brand names, Dextroproxifeno Analogs
Dextroproxifeno Brand Names Mixture
- No information avaliable
Dextroproxifeno Chemical_Formula
C22H29NO2
Dextroproxifeno RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Dextroproxifeno fda sheet
Dextroproxifeno msds (material safety sheet)
Dextroproxifeno Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Dextroproxifeno Molecular Weight
339.471 g/mol
Dextroproxifeno Melting Point
75-76oC
Dextroproxifeno H2O Solubility
19.6mg/L
Dextroproxifeno State
Solid
Dextroproxifeno LogP
4.901
Dextroproxifeno Dosage Forms
Tablet
Dextroproxifeno Indication
For the relief of mild to moderate pain
Dextroproxifeno Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Dextroproxifeno Absorption
No information avaliable
Dextroproxifeno side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Dextroproxifeno Patient Information
Dextroproxifeno Organisms Affected
Humans and other mammals
