Erantin
Brand names,
Erantin
Analogs
Erantin
Brand Names Mixture
Erantin
Chemical_Formula
C22H29NO2
Erantin
RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Erantin
fda sheet
Erantin
msds (material safety sheet)
Erantin
Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Erantin
Molecular Weight
339.471 g/mol
Erantin
Melting Point
75-76oC
Erantin
H2O Solubility
19.6mg/L
Erantin
State
Solid
Erantin
LogP
4.901
Erantin
Dosage Forms
Tablet
Erantin
Indication
For the relief of mild to moderate pain
Erantin
Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Erantin
Absorption
No information avaliable
Erantin
side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Erantin
Patient Information
Erantin
Organisms Affected
Humans and other mammals