Propoxyphene HCl
Propoxyphene HCl Brand names, Propoxyphene HCl Analogs
Propoxyphene HCl Brand Names Mixture
- No information avaliable
Propoxyphene HCl Chemical_Formula
C22H29NO2
Propoxyphene HCl RX_link
http://www.rxlist.com/cgi/generic/propox.htm
Propoxyphene HCl fda sheet
Propoxyphene HCl msds (material safety sheet)
Propoxyphene HCl Synthesis Reference
Pohland, U.S. Pat. 2,728,779 (1955)
Propoxyphene HCl Molecular Weight
339.471 g/mol
Propoxyphene HCl Melting Point
75-76oC
Propoxyphene HCl H2O Solubility
19.6mg/L
Propoxyphene HCl State
Solid
Propoxyphene HCl LogP
4.901
Propoxyphene HCl Dosage Forms
Tablet
Propoxyphene HCl Indication
For the relief of mild to moderate pain
Propoxyphene HCl Pharmacology
Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads to a decrease of the perception of pain stimuli.
Propoxyphene HCl Absorption
No information avaliable
Propoxyphene HCl side effects and Toxicity
Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more frequently in patients with propoxyphene intoxication than in those with opiate intoxication. LD50=230mg/kg (orally in rat, Emerson)
Propoxyphene HCl Patient Information
Propoxyphene HCl Organisms Affected
Humans and other mammals
