PharmacyCodes



Nystatin sodium en es it fr

Nystatin sodium Brand names, Nystatin sodium Analogs

Nystatin sodium Brand Names Mixture

  • No information avaliable

Nystatin sodium Chemical_Formula

C47H75NO17

Nystatin sodium RX_link

http://www.rxlist.com/cgi/generic2/nystat.htm

Nystatin sodium fda sheet

Nystatin_sodium FDA

Nystatin sodium msds (material safety sheet)

Nystatin_sodium MSDS

Nystatin sodium Synthesis Reference

No information avaliable

Nystatin sodium Molecular Weight

926.09 g/mol

Nystatin sodium Melting Point

160oC

Nystatin sodium H2O Solubility

360 mg/L

Nystatin sodium State

Solid

Nystatin sodium LogP

-0.534

Nystatin sodium Dosage Forms

Cream; Drops; Liquid; Ointment; Suspension; Tablet

Nystatin sodium Indication

For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species

Nystatin sodium Pharmacology

Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.

Nystatin sodium Absorption

Nystatin is not absorbed from intact skin or mucous membrane

Nystatin sodium side effects and Toxicity

No information avaliable

Nystatin sodium Patient Information

No information avaliable

Nystatin sodium Organisms Affected

Fungi