Nyaderm
Nyaderm Brand names, Nyaderm Analogs
Nyaderm Brand Names Mixture
- No information avaliable
Nyaderm Chemical_Formula
C47H75NO17
Nyaderm RX_link
http://www.rxlist.com/cgi/generic2/nystat.htm
Nyaderm fda sheet
Nyaderm msds (material safety sheet)
Nyaderm Synthesis Reference
No information avaliable
Nyaderm Molecular Weight
926.09 g/mol
Nyaderm Melting Point
160oC
Nyaderm H2O Solubility
360 mg/L
Nyaderm State
Solid
Nyaderm LogP
-0.534
Nyaderm Dosage Forms
Cream; Drops; Liquid; Ointment; Suspension; Tablet
Nyaderm Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
Nyaderm Pharmacology
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
Nyaderm Absorption
Nystatin is not absorbed from intact skin or mucous membrane
Nyaderm side effects and Toxicity
No information avaliable
Nyaderm Patient Information
No information avaliable
Nyaderm Organisms Affected
Fungi
