Mytrex F
Mytrex F Brand names, Mytrex F Analogs
Mytrex F Brand Names Mixture
- No information avaliable
Mytrex F Chemical_Formula
C47H75NO17
Mytrex F RX_link
http://www.rxlist.com/cgi/generic2/nystat.htm
Mytrex F fda sheet
Mytrex F msds (material safety sheet)
Mytrex F Synthesis Reference
No information avaliable
Mytrex F Molecular Weight
926.09 g/mol
Mytrex F Melting Point
160oC
Mytrex F H2O Solubility
360 mg/L
Mytrex F State
Solid
Mytrex F LogP
-0.534
Mytrex F Dosage Forms
Cream; Drops; Liquid; Ointment; Suspension; Tablet
Mytrex F Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
Mytrex F Pharmacology
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
Mytrex F Absorption
Nystatin is not absorbed from intact skin or mucous membrane
Mytrex F side effects and Toxicity
No information avaliable
Mytrex F Patient Information
No information avaliable
Mytrex F Organisms Affected
Fungi
