Mycolog-Ii
Mycolog-Ii Brand names, Mycolog-Ii Analogs
Mycolog-Ii Brand Names Mixture
- No information avaliable
Mycolog-Ii Chemical_Formula
C47H75NO17
Mycolog-Ii RX_link
http://www.rxlist.com/cgi/generic2/nystat.htm
Mycolog-Ii fda sheet
Mycolog-Ii msds (material safety sheet)
Mycolog-Ii Synthesis Reference
No information avaliable
Mycolog-Ii Molecular Weight
926.09 g/mol
Mycolog-Ii Melting Point
160oC
Mycolog-Ii H2O Solubility
360 mg/L
Mycolog-Ii State
Solid
Mycolog-Ii LogP
-0.534
Mycolog-Ii Dosage Forms
Cream; Drops; Liquid; Ointment; Suspension; Tablet
Mycolog-Ii Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
Mycolog-Ii Pharmacology
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
Mycolog-Ii Absorption
Nystatin is not absorbed from intact skin or mucous membrane
Mycolog-Ii side effects and Toxicity
No information avaliable
Mycolog-Ii Patient Information
No information avaliable
Mycolog-Ii Organisms Affected
Fungi
