Nystop
Nystop Brand names, Nystop Analogs
Nystop Brand Names Mixture
- No information avaliable
Nystop Chemical_Formula
C47H75NO17
Nystop RX_link
http://www.rxlist.com/cgi/generic2/nystat.htm
Nystop fda sheet
Nystop msds (material safety sheet)
Nystop Synthesis Reference
No information avaliable
Nystop Molecular Weight
926.09 g/mol
Nystop Melting Point
160oC
Nystop H2O Solubility
360 mg/L
Nystop State
Solid
Nystop LogP
-0.534
Nystop Dosage Forms
Cream; Drops; Liquid; Ointment; Suspension; Tablet
Nystop Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
Nystop Pharmacology
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
Nystop Absorption
Nystatin is not absorbed from intact skin or mucous membrane
Nystop side effects and Toxicity
No information avaliable
Nystop Patient Information
No information avaliable
Nystop Organisms Affected
Fungi
