Nystex
Nystex Brand names, Nystex Analogs
Nystex Brand Names Mixture
- No information avaliable
Nystex Chemical_Formula
C47H75NO17
Nystex RX_link
http://www.rxlist.com/cgi/generic2/nystat.htm
Nystex fda sheet
Nystex msds (material safety sheet)
Nystex Synthesis Reference
No information avaliable
Nystex Molecular Weight
926.09 g/mol
Nystex Melting Point
160oC
Nystex H2O Solubility
360 mg/L
Nystex State
Solid
Nystex LogP
-0.534
Nystex Dosage Forms
Cream; Drops; Liquid; Ointment; Suspension; Tablet
Nystex Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
Nystex Pharmacology
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
Nystex Absorption
Nystatin is not absorbed from intact skin or mucous membrane
Nystex side effects and Toxicity
No information avaliable
Nystex Patient Information
No information avaliable
Nystex Organisms Affected
Fungi
