Sodium nystatin
Sodium nystatin Brand names, Sodium nystatin Analogs
Sodium nystatin Brand Names Mixture
- No information avaliable
Sodium nystatin Chemical_Formula
C47H75NO17
Sodium nystatin RX_link
http://www.rxlist.com/cgi/generic2/nystat.htm
Sodium nystatin fda sheet
Sodium nystatin msds (material safety sheet)
Sodium nystatin Synthesis Reference
No information avaliable
Sodium nystatin Molecular Weight
926.09 g/mol
Sodium nystatin Melting Point
160oC
Sodium nystatin H2O Solubility
360 mg/L
Sodium nystatin State
Solid
Sodium nystatin LogP
-0.534
Sodium nystatin Dosage Forms
Cream; Drops; Liquid; Ointment; Suspension; Tablet
Sodium nystatin Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
Sodium nystatin Pharmacology
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
Sodium nystatin Absorption
Nystatin is not absorbed from intact skin or mucous membrane
Sodium nystatin side effects and Toxicity
No information avaliable
Sodium nystatin Patient Information
No information avaliable
Sodium nystatin Organisms Affected
Fungi
