Myco-Triacet Ii
Brand names,
Myco-Triacet Ii
Analogs
Myco-Triacet Ii
Brand Names Mixture
Myco-Triacet Ii
Chemical_Formula
C47H75NO17
Myco-Triacet Ii
RX_link
http://www.rxlist.com/cgi/generic2/nystat.htm
Myco-Triacet Ii
fda sheet
Myco-Triacet Ii
msds (material safety sheet)
Myco-Triacet Ii
Synthesis Reference
No information avaliable
Myco-Triacet Ii
Molecular Weight
926.09 g/mol
Myco-Triacet Ii
Melting Point
160oC
Myco-Triacet Ii
H2O Solubility
360 mg/L
Myco-Triacet Ii
State
Solid
Myco-Triacet Ii
LogP
-0.534
Myco-Triacet Ii
Dosage Forms
Cream; Drops; Liquid; Ointment; Suspension; Tablet
Myco-Triacet Ii
Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
Myco-Triacet Ii
Pharmacology
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
Myco-Triacet Ii
Absorption
Nystatin is not absorbed from intact skin or mucous membrane
Myco-Triacet Ii
side effects and Toxicity
No information avaliable
Myco-Triacet Ii
Patient Information
No information avaliable
Myco-Triacet Ii
Organisms Affected
Fungi