nystatin dihydrate
nystatin dihydrate Brand names, nystatin dihydrate Analogs
nystatin dihydrate Brand Names Mixture
- No information avaliable
nystatin dihydrate Chemical_Formula
C47H75NO17
nystatin dihydrate RX_link
http://www.rxlist.com/cgi/generic2/nystat.htm
nystatin dihydrate fda sheet
nystatin dihydrate msds (material safety sheet)
nystatin dihydrate Synthesis Reference
No information avaliable
nystatin dihydrate Molecular Weight
926.09 g/mol
nystatin dihydrate Melting Point
160oC
nystatin dihydrate H2O Solubility
360 mg/L
nystatin dihydrate State
Solid
nystatin dihydrate LogP
-0.534
nystatin dihydrate Dosage Forms
Cream; Drops; Liquid; Ointment; Suspension; Tablet
nystatin dihydrate Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
nystatin dihydrate Pharmacology
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
nystatin dihydrate Absorption
Nystatin is not absorbed from intact skin or mucous membrane
nystatin dihydrate side effects and Toxicity
No information avaliable
nystatin dihydrate Patient Information
No information avaliable
nystatin dihydrate Organisms Affected
Fungi
