Barstatin 100
Brand names,
Barstatin 100
Analogs
Barstatin 100
Brand Names Mixture
Barstatin 100
Chemical_Formula
C47H75NO17
Barstatin 100
RX_link
http://www.rxlist.com/cgi/generic2/nystat.htm
Barstatin 100
fda sheet
Barstatin 100
msds (material safety sheet)
Barstatin 100
Synthesis Reference
No information avaliable
Barstatin 100
Molecular Weight
926.09 g/mol
Barstatin 100
Melting Point
160oC
Barstatin 100
H2O Solubility
360 mg/L
Barstatin 100
State
Solid
Barstatin 100
LogP
-0.534
Barstatin 100
Dosage Forms
Cream; Drops; Liquid; Ointment; Suspension; Tablet
Barstatin 100
Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
Barstatin 100
Pharmacology
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
Barstatin 100
Absorption
Nystatin is not absorbed from intact skin or mucous membrane
Barstatin 100
side effects and Toxicity
No information avaliable
Barstatin 100
Patient Information
No information avaliable
Barstatin 100
Organisms Affected
Fungi