Mycostatin
Mycostatin Brand names, Mycostatin Analogs
Mycostatin Brand Names Mixture
- No information avaliable
Mycostatin Chemical_Formula
C47H75NO17
Mycostatin RX_link
http://www.rxlist.com/cgi/generic2/nystat.htm
Mycostatin fda sheet
Mycostatin msds (material safety sheet)
Mycostatin Synthesis Reference
No information avaliable
Mycostatin Molecular Weight
926.09 g/mol
Mycostatin Melting Point
160oC
Mycostatin H2O Solubility
360 mg/L
Mycostatin State
Solid
Mycostatin LogP
-0.534
Mycostatin Dosage Forms
Cream; Drops; Liquid; Ointment; Suspension; Tablet
Mycostatin Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
Mycostatin Pharmacology
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
Mycostatin Absorption
Nystatin is not absorbed from intact skin or mucous membrane
Mycostatin side effects and Toxicity
No information avaliable
Mycostatin Patient Information
No information avaliable
Mycostatin Organisms Affected
Fungi
