PMS Nystatin
PMS Nystatin Brand names, PMS Nystatin Analogs
PMS Nystatin Brand Names Mixture
- No information avaliable
PMS Nystatin Chemical_Formula
C47H75NO17
PMS Nystatin RX_link
http://www.rxlist.com/cgi/generic2/nystat.htm
PMS Nystatin fda sheet
PMS Nystatin msds (material safety sheet)
PMS Nystatin Synthesis Reference
No information avaliable
PMS Nystatin Molecular Weight
926.09 g/mol
PMS Nystatin Melting Point
160oC
PMS Nystatin H2O Solubility
360 mg/L
PMS Nystatin State
Solid
PMS Nystatin LogP
-0.534
PMS Nystatin Dosage Forms
Cream; Drops; Liquid; Ointment; Suspension; Tablet
PMS Nystatin Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
PMS Nystatin Pharmacology
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
PMS Nystatin Absorption
Nystatin is not absorbed from intact skin or mucous membrane
PMS Nystatin side effects and Toxicity
No information avaliable
PMS Nystatin Patient Information
No information avaliable
PMS Nystatin Organisms Affected
Fungi
