Nystatin-Triamcinolone Acetonide
Brand names,
Nystatin-Triamcinolone Acetonide
Analogs
Nystatin-Triamcinolone Acetonide
Brand Names Mixture
Nystatin-Triamcinolone Acetonide
Chemical_Formula
C47H75NO17
Nystatin-Triamcinolone Acetonide
RX_link
http://www.rxlist.com/cgi/generic2/nystat.htm
Nystatin-Triamcinolone Acetonide
fda sheet
Nystatin-Triamcinolone Acetonide
msds (material safety sheet)
Nystatin-Triamcinolone Acetonide
Synthesis Reference
No information avaliable
Nystatin-Triamcinolone Acetonide
Molecular Weight
926.09 g/mol
Nystatin-Triamcinolone Acetonide
Melting Point
160oC
Nystatin-Triamcinolone Acetonide
H2O Solubility
360 mg/L
Nystatin-Triamcinolone Acetonide
State
Solid
Nystatin-Triamcinolone Acetonide
LogP
-0.534
Nystatin-Triamcinolone Acetonide
Dosage Forms
Cream; Drops; Liquid; Ointment; Suspension; Tablet
Nystatin-Triamcinolone Acetonide
Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
Nystatin-Triamcinolone Acetonide
Pharmacology
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
Nystatin-Triamcinolone Acetonide
Absorption
Nystatin is not absorbed from intact skin or mucous membrane
Nystatin-Triamcinolone Acetonide
side effects and Toxicity
No information avaliable
Nystatin-Triamcinolone Acetonide
Patient Information
No information avaliable
Nystatin-Triamcinolone Acetonide
Organisms Affected
Fungi