PharmacyCodes



Nystatin en es it fr

Nystatin Brand names, Nystatin Analogs

Nystatin Brand Names Mixture

  • No information avaliable

Nystatin Chemical_Formula

C47H75NO17

Nystatin RX_link

http://www.rxlist.com/cgi/generic2/nystat.htm

Nystatin fda sheet

Nystatin FDA

Nystatin msds (material safety sheet)

Nystatin MSDS

Nystatin Synthesis Reference

No information avaliable

Nystatin Molecular Weight

926.09 g/mol

Nystatin Melting Point

160oC

Nystatin H2O Solubility

360 mg/L

Nystatin State

Solid

Nystatin LogP

-0.534

Nystatin Dosage Forms

Cream; Drops; Liquid; Ointment; Suspension; Tablet

Nystatin Indication

For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species

Nystatin Pharmacology

Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.

Nystatin Absorption

Nystatin is not absorbed from intact skin or mucous membrane

Nystatin side effects and Toxicity

No information avaliable

Nystatin Patient Information

No information avaliable

Nystatin Organisms Affected

Fungi