Nystatin, sodium salt
Nystatin, sodium salt Brand names, Nystatin, sodium salt Analogs
Nystatin, sodium salt Brand Names Mixture
- No information avaliable
Nystatin, sodium salt Chemical_Formula
C47H75NO17
Nystatin, sodium salt RX_link
http://www.rxlist.com/cgi/generic2/nystat.htm
Nystatin, sodium salt fda sheet
Nystatin, sodium salt msds (material safety sheet)
Nystatin, sodium salt Synthesis Reference
No information avaliable
Nystatin, sodium salt Molecular Weight
926.09 g/mol
Nystatin, sodium salt Melting Point
160oC
Nystatin, sodium salt H2O Solubility
360 mg/L
Nystatin, sodium salt State
Solid
Nystatin, sodium salt LogP
-0.534
Nystatin, sodium salt Dosage Forms
Cream; Drops; Liquid; Ointment; Suspension; Tablet
Nystatin, sodium salt Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
Nystatin, sodium salt Pharmacology
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
Nystatin, sodium salt Absorption
Nystatin is not absorbed from intact skin or mucous membrane
Nystatin, sodium salt side effects and Toxicity
No information avaliable
Nystatin, sodium salt Patient Information
No information avaliable
Nystatin, sodium salt Organisms Affected
Fungi
