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Meperidine Brand names, Meperidine Analogs

Meperidine Brand Names Mixture

  • No information avaliable

Meperidine Chemical_Formula

C15H21NO2

Meperidine RX_link

http://www.rxlist.com/cgi/generic/meper.htm

Meperidine fda sheet

Meperidine FDA

Meperidine msds (material safety sheet)

Meperidine MSDS

Meperidine Synthesis Reference

No information avaliable

Meperidine Molecular Weight

247.333 g/mol

Meperidine Melting Point

186 - 189 oC

Meperidine H2O Solubility

3220 mg/L

Meperidine State

Solid

Meperidine LogP

3.303

Meperidine Dosage Forms

Syrup; Tablet

Meperidine Indication

Used to control moderate to severe pain.

Meperidine Pharmacology

Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.

Meperidine Absorption

Oral bioavailability is 50-60% in patients with normal hepatic function.

Meperidine side effects and Toxicity

No information avaliable

Meperidine Patient Information

No information avaliable

Meperidine Organisms Affected

Humans and other mammals