Meperidine
Meperidine Brand names, Meperidine Analogs
Meperidine Brand Names Mixture
- No information avaliable
Meperidine Chemical_Formula
C15H21NO2
Meperidine RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Meperidine fda sheet
Meperidine msds (material safety sheet)
Meperidine Synthesis Reference
No information avaliable
Meperidine Molecular Weight
247.333 g/mol
Meperidine Melting Point
186 - 189 oC
Meperidine H2O Solubility
3220 mg/L
Meperidine State
Solid
Meperidine LogP
3.303
Meperidine Dosage Forms
Syrup; Tablet
Meperidine Indication
Used to control moderate to severe pain.
Meperidine Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Meperidine Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Meperidine side effects and Toxicity
No information avaliable
Meperidine Patient Information
No information avaliable
Meperidine Organisms Affected
Humans and other mammals
