Dolosal
Dolosal Brand names, Dolosal Analogs
Dolosal Brand Names Mixture
- No information avaliable
Dolosal Chemical_Formula
C15H21NO2
Dolosal RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Dolosal fda sheet
Dolosal msds (material safety sheet)
Dolosal Synthesis Reference
No information avaliable
Dolosal Molecular Weight
247.333 g/mol
Dolosal Melting Point
186 - 189 oC
Dolosal H2O Solubility
3220 mg/L
Dolosal State
Solid
Dolosal LogP
3.303
Dolosal Dosage Forms
Syrup; Tablet
Dolosal Indication
Used to control moderate to severe pain.
Dolosal Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Dolosal Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Dolosal side effects and Toxicity
No information avaliable
Dolosal Patient Information
No information avaliable
Dolosal Organisms Affected
Humans and other mammals
