Dolcontral
Brand names,
Dolcontral
Analogs
Dolcontral
Brand Names Mixture
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Chemical_Formula
C15H21NO2
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RX_link
http://www.rxlist.com/cgi/generic/meper.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
247.333 g/mol
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Melting Point
186 - 189 oC
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H2O Solubility
3220 mg/L
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State
Solid
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LogP
3.303
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Dosage Forms
Syrup; Tablet
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Indication
Used to control moderate to severe pain.
Dolcontral
Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Dolcontral
Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
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side effects and Toxicity
No information avaliable
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals